Hipsec predicts if gene overexpression of an extracellular protein will lead to successful high-level production in Aspergillus niger. The prediction is based on a protein's amino acid sequence. A fasta file with one or more protein sequences can be pasted into the the text area or uploaded using the 'Choose File' button. Click the 'Submit' button to run the prediction method. More information about the method can be found in the corresponding paper (1).